![]() ![]() ![]() In environments with artificial lighting humans are rarely dark-adapted, hence cone function becomes critical. But light needs to be delivered at specific times. ![]() We show here that single 3 min 670 nm exposures, at much lower energies than previously used, are sufficient to significantly improve for 1 week cone mediated colour contrast thresholds (detection) in ageing populations (37–70 years) to levels associated with younger subjects. ![]() Recently, repeated 670 nm exposures have been used on the aged human retina, which has high-energy demands and significant mitochondrial and functional decline, to improve vision. The likely mechanism is via long wavelengths reducing nanoscopic interfacial water viscosity around ATP rota pumps, improving their efficiency. However, animal studies show that long wavelength exposure (650–900 nm) over weeks partially restores ATP and improves function. Mitochondrial decline in ageing robs cells of ATP.
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